Lets see...
1 Try stamps, and also try to modify them
2 as firsts, do not make so big arts (like not a 250x250, first try idk, 50x50)
3 have a clear idea of what to do
4 NO 3D THINGS they are impossible
5 have fun :D
I agree with formulao try to use stamps and modify them
And yes 3d pixil arts are hard but if u use grids it makes it easier
Always fill in the background
And if tyour making a huge drawing always remember you can zoom in
What do you think?